4(3H)-pyrimidinone, 6-amino-5-nitro- - Names and Identifiers
4(3H)-pyrimidinone, 6-amino-5-nitro- - Physico-chemical Properties
Molecular Formula | C4H4N4O3
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Molar Mass | 156.1 |
Density | 2.02g/cm3 |
Boling Point | 228.9°C at 760 mmHg |
Flash Point | 92.3°C |
Vapor Presure | 0.0715mmHg at 25°C |
Refractive Index | 1.798 |
4(3H)-pyrimidinone, 6-amino-5-nitro- - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
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HS Code | 29335990 |
4(3H)-pyrimidinone, 6-amino-5-nitro- - Introduction
6-amino-5-nitropyrimidin-4(1H)-one(6-amino-5-nitropyrimidin-4(1H)-one) is an organic compound with the chemical formula C4H3N5O3.
Nature:
-Appearance: White or light yellow crystal powder;
-Melting point: 189-192°C;
-Solubility: Slightly soluble in water, methanol and alcohol solvents.
Use:
-Intermediate: 6-amino-5-nitropyrimidin-4(1H)-one is an intermediate for the synthesis of anti-tumor drugs and biologically active compounds;
-Chemical research: can be used as catalysts, catalysts for organic synthesis reactions, important substrates or reagents.
Preparation Method:
6-amino-5-nitropyrimidin-4(1H)-one has many synthesis methods, and the commonly used methods are through nitration and reduction reactions.
The specific steps are as follows:
1.6-amino -4-hydroxyl pyrimidine reaction with concentrated nitric acid, stirring in ice.
2. The reaction product was filtered, washed and dried to give 6-amino-5-nitropyrimidin-4(1H)-one.
Safety Information:
Reliable data are currently available on the toxicity and safety of 6-amino-5-nitropyrimidin-4(1H)-one. These compounds are generally organic synthesis intermediates and should be handled in accordance with appropriate chemical laboratory practices, following the recommended procedures in the relevant safety manual. For further information on toxicity and safety, consult a reliable chemical safety database or consult an expert.
Last Update:2024-04-09 21:54:55